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JAI RESEARCH FOUNDATION |
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INTRODUCTION |
JRF is a India OECD GLP Laboratory. Winhonor work on behalf of them since November 2012.
JRF Is A Multidisciplinary Contract Research Organization, in 42th year of its operation ( Established in 1977).
JRF is Dedicated to Contract Research in the Fields of Toxicology, Eco-toxicology, Chemistry, Environmental Fate & Metabolism, in Conformity with the Regulatory Guidelines.
Offers Contract Research Services to a plethora of Industrial sectors including Agrochem, Pharma, Biocides, Food & Speciality Chemicals.
Buildings : 15,000 Sq. M.
Manpower: Total -200 (250); Scientific staff – 120 (150)
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ORGANIZATION |
JRF GLOBAL CONTENTS:
1. JRF INDIA
COMPREHENSIVE TOXICOLOGY,
PRODUCT CHEMISTRY,
E-FATE
2. JRF AMERICA
E-FATE,
EFFICACY,
EXPOSURE,
RESIDUE,
CHEMISTRY
3. GC LABORATORIES
PRODUCT,
4. JRF INTERNATIONAL
REGULATORY CONSULTANCY
REACH,
5-B,
EFFICACY TRIALS,
RESIDUE TRIALS,
RESIDUE,
CHEMISTRY
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JRF集团包含:
1. 印度JRF实验室
综合毒理学,
产品化学,
环境行为
2. 美国JRF实验室
环境行为,
药效实验,
暴露实验,
残留实验,
化学分析
3. 英国JRF实验室
产品
4. 英国JRF咨询服务公司
法规咨询,
REACH,
5批次,
药效试验,
残留实验,
残留,
化学分析
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OBJECTIVES |
1. AGRICULTURAL CHEMICALS
2. FOODS
3. PHARMACEUTICALS
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1. 农化产品
2. 食品
3. 医药产品
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JRF INDIA |
1. Comprehensive Toxicology
1.1 Acute,
1.2 Chronic and Developmental and Genetic Toxicity,
1.3 EDSP
2. Product Chemistry
2.1 5 BA
2.2 Phys-chem
2.3 MD-MV
3. E-fate & Ecotox
4. Regulatory Consultancy & REACH |
1. 综合毒理
1.1 急性
1.2 慢性, 发育和遗传毒性
1.3 EDSP
2. 产品化学
2.1 5批次
2.2 理化
2.3 分析方法建立和验证
3. 环境行为和环境毒性
4. 登记咨询和REACH |
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TOXICITY
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TEST METHOD |
TEST |
1. ACUTE STUDIES |
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420 |
Acute Oral Toxicity, Mouse / Rat |
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423 |
Acute Oral Toxicity, Mouse / Rat |
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425 |
Acute Oral Toxicity, Mouse / Rat |
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402 |
Acute Dermal Toxicity, Rat |
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403 |
Acute Inhalation Toxicity, Rat |
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404 |
Acute Dermal Irritation / Corrosion, Rabbit |
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405 |
Acute Eye Irritation / Corrosion, Rabbit |
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406 |
Skin Sensitisation - Guinea pig (Buehler Test) |
2. SUBCHRONIC STUDIES |
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407 |
Repeated Dose Oral Toxicity - Rodent : 28 - Day |
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408 |
Subchronic Oral Toxicity - Rodent : 90 - Day |
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Chronic Toxicity Study – Rodent : 180 - Day |
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410 |
Repeated Dose Dermal Toxicity : 21 / 28 - Day |
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411 |
Subchronic Dermal Toxicity : 90 – Day |
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414 |
Teratogenicity, Rat |
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Teratogenicity, Rabbit |
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415 |
One - Generation Reproduction Toxicity Study |
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416 |
Two - Generation Reproduction Toxicity Study |
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418 |
Acute Delayed Neurotoxicity of Organophosphorous Substances |
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422 |
Reproduction / Developmental Toxicity Screening Test |
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451 |
Carcinogenicity Study - Mouse |
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Carcinogenicity Study - Rat |
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452 |
Chronic Toxicity Study – Rodent (1 Year) |
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453 |
Combined Chronic Toxicity / Carcinogenicity Study – Rodent |
3. GENETIC TOXICOLOGY |
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471 |
Salmonella typhimurium, Reverse Mutation Assay (Ames Test) |
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473 |
In vitro Mammalian Cytogenetic Test |
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474 |
Micronucleus Test |
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475 |
In vivo Mammalian Bone Marrow Cytogenetic Test - Chromosomal Analysis |
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476 |
In vitro Mammalian Cell Gene Mutation Test |
4. ECOTOXICITY |
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201 |
Alga, Growth Inhibition Test |
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202 a |
Daphnia sp., Acute Immobilization Test |
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203 |
Fish, Acute Toxicity Test |
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205 |
Avian Dietary Toxicity Test |
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206 |
Avian Reproduction Test |
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207 |
Earthworm, Acute Toxicity Tests |
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213 |
Honey bee, oral toxicity |
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214 |
Honey bee, contact toxicity |
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OPPTS |
Toxicity to birds (Acute Oral – Japanese quail) |
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Avian Acute Oral Toxicity Test |
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Other test as customers requirement |
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Phy&Chem
物化性质实验
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TEST METHOD |
TEST |
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OPPTS |
Physical State |
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OPPTS |
Color. |
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OPPTS |
Odor |
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OECD 102 |
Melting Point |
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Boling Point: (Liquids at room temperature:) OECD 103. |
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OECD 109- CIPAC MT3 |
Density: OECD 109- CIPAC MT 3/ MT 58.4. |
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OECD 104 |
Vapor pressure: OECD 104.ã |
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Not offered presently |
Volatility. ã |
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Solubility in Water: OECD 105; CIPAC MT 157.1 y 157.2. ã (at single pH) |
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Absorption Spectrums of active ingredient. * Two of:
2.7.1 IR (infra red) and/or
2.7.2 NMR (Nuclear Magnectic Resonance) or
2.7.3 MS (Mass Spectophotometry) |
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OECD 105 |
Solubilidad en solventes orgánicos |
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OECD 107, OECD 117 |
N-octanol/water coefficient partition:OECD117, FIFRA63-11. ã |
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Stability in Water: OECD 111. ã |
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CIPAC MT 12 |
Flammability: Flash Point: CIPAC MT 12. |
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OECD 115; EEC A5 |
Superficial tension: OECD 115 EEC A5. |
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Explosive properties: EEC A. 14; FIFRA 63-16ã |
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FIFRA 63-20 |
Oxydizing properties: (corrosivity).- EEC A17; FIFRA 63-20. |
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FIFRA 63-20 |
Reactivity with packaging material: FIFRA 63-20. |
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CIPAC MT75; FIFRA 63-12 |
pH: CIPAC MT 75; FIFRA 63-12. |
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Water dissociation constant: OECD 112; FIFRA 63-10. ã |
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CIPAC MT 22. |
Viscosidad: (para sustancias líquidas). CIPAC MT 22. |
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Other test as customers requirement |
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